Mouse syngeneic monoclonal anti-idiotypic antibody to okadaic acid
| Erfa Biotech | |
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Mouse syngeneic monoclonal anti-idiotypic antibody to okadaic acid |
Mouse syngeneic monoclonal
anti-idiotypic antibody to okadaic acid
(FOR
RESEARCH)
TRADE NAME: 1/59-2
The antibody was produced from polyethylene glycol fusion of non-secreting mouse
myeloma(P3X63.Ag.8.653) cells with spleen cells from Balb/c mouse immunized
with anti-okadaic acid mouse monoclonal antibody.
ANTIBODY CHARACTERISTICS
| Immunoglobulin class : | IgG1,
k |
| Immunologic specificity : | The
antibody is an internal image of okadaic acid. In ELISA, it inhibits the
binding of both okadaic acid to solid-phase bound F(ab')2 fragments of
anti-OA monoclonal antibody 6/50-26 and 6/50 IgG to solid-phase bound OA.
It also induces production of okadaic acid binding Ab3 antibodies in
Balb/c mice and inhibits the catalytic subunits of serine-threonine
protein phosphatases PP1 and PP2A. |
| Cross-reactivity : | It
does not cross-react with F(ab')2 fragments from normal mouse pooled serum
IgG in ELISA. |
| Use : Basic research. | May
be used as a surrogate of okadaic acid in certain functional assays such
as inhibition of protein phosphatases PP1/PP2 or in ELISA for quantitation
of okadaic acid. When bound to a solid support (e.g. CNBr activated
Sepharose 4B) it can be used for purification of protein phosphastases
PP1/PP2. |
| Storage: | Store
at 4oC. |
| Stability : | When
reconstituted in aqueous solution IgG, remains stable for six months if
stored at 4oC. No considerable loss of activity was detected
when stored at -20oC over a period of one year. |
| Delivery form : | Lyophilized
pure IgG (ascites derived) |
| Delivery quantities : | - 1
mg/vial SKU #: 76400 - 5 mg/vial SKU #: 76405 - 10 mg/vial Catalog No.: 76410 |